GASTRIC BYPASS CAUSES WEIGHT LOSS AND REMISSION OF DIABETES AND NASH


The EndoSleeve is a proprietary implant that anchors at the junction of the stomach and small intestine (the pyloric sphincter).  The sleeve component of the implant channels food from the stomach and bypasses a portion of the small intestine. 


Because the food is blocked from contacting the first part of the smalll intestine and the bile and pancreatic secretions flow around the sleeve it leads to identical neuro-hormonal signaling changes in the intestine to gastric bypass surgery. This quickly leads to the remission of Type 2 Diabetes and NASH and also over time causes significant weight loss.

The procedure doctors use to place the EndoSleeve is similar to a routine GI endoscopy and can be performed under conscious sedation.  The tools and techniques involved are familiar to gastroenterologists, endoscopic surgeons, and interventional radiologists. The procedure will take less than 30 minutes to perform and the patient return home the same day. 

OUR SOLUTION PROVIDES AN ALTERNATIVE TO SURGERY



In the past 10 years, researchers discovered that gastric bypass surgery, in which a portion of the stomach and small intestine is bypassed, results in remission of T2DM in addition to the expected weight loss.  This breakthrough has provided a meaningful alternative for obese patients struggling to manage their diabetes.  The American Diabetes Association now recommends gastric bypass surgery as a treatment option for patients with diabetes

Unfortunately, the benefits provided by this procedure are limited to only a fraction of people living with Type 2 Diabetes.  Currently, bariatric surgery is reserved for only morbidly obese patients due to the fact that is risky (0.5% - 2% mortality), expensive ($35,000), and invasive (1 week hospital stay and lifelong changes in diet) .


The surgery also leads to amelioration of NASH a severe form of non-alcoholic fatty liver disease which mostly goes undiagnosed but can lead to serious complications such as liver failure